Healing Effect and Underlying Mechanism of Silver Nanoparticles Prepared Using Carboxymethyl Chitosan under Solar Irradiation

In our previous study, silver nanoparticles were prepared using AgNO3 and carboxymethyl chitosan (CMCS) which is commercially available with solar irradiation. this the efficacy safety of by method evaluated for healing wounds in rats diabetes. We also attempted to determine underlying mechanism influencing factors nanomaterial preparation method. Compared growth factors, exhibit better effects No remnant ions detected major organs these after application nanoparticles. Silver CMCS are less toxic than those from conventional method, promote proliferation skin fibroblasts, promising as a topical medication infected wounds. An obvious breakage process particles observed during nanocrystalline CMCS. we whether suitable synthesizing N-trimethyl chloride sodium alginate used particular experiment. The characteristic UV-vis absorbance peak was found only reaction mixture containing chloride. Our study demonstrates that free radicals key factor nanoparticle